Preparation and Characterization of Serratiopeptidase Containing Microspheres

نویسندگان

  • J. S. Dua
  • A. C. Rana
  • A. K. Bhandari
چکیده

In the study we formulated the serratiopeptidase loaded cholic acid conjugated and unconjugated chitosan mucoadhesive microspheres. It was observed that the conjugated microspheres show better permeation rate than unconjugated microspheres. Moreover the permeation enhancer increased the % cumulative drug permeation through the mucosal membrane from 69.37 % to 74.39 % for unconjugated microspheres and conjugated microspheres respectively.

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تاریخ انتشار 2014